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2025

Pharmacological Insights of Mahakashaya
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Pharmacological Insights into Charakokta Dashemani: Karmas, Rasa, Guna, Vipaka, Veerya, Dosha Karma, and Therapeutic Potential Part -3 (21- 30 Dashemani Mahakashaya)

21. Snehopaga Mahakashaya Varga (Adjuvants of Oleation Therapy) Introduction The Snehopaga Mahakashaya Varga consists of ten medicinal plants that act as adjuvants in Snehana Karma (Oleation Therapy). These herbs enhance the properties of medicated oils and ghee, supporting deep tissue nourishment, lubrication, and detoxification. They help in balancing Vata and Pitta Dosha, improving the absorption of Sneha Dravyas, and promoting rejuvenation and vitality. List of Snehopaga Dravyas (Medicinal Plants of Snehopaga Varga) SI No Name Botanical Name Rasa (Taste) Guna (Properties) Vipaka (Post-digestive effect) Virya (Potency) Active Compounds 1 Mradwika Vitis vinifera Madhura Guru, Snigdha Madhura Shita Resveratrol, Flavonoids 2 Madhuka Glycyrrhiza glabra Madhura Guru, Snigdha Madhura Shita Glycyrrhizin, Flavonoids 3 Madhuparni Tinospora cordifolia Tikta, Kashaya Guru, Snigdha Madhura Ushna Tinosporin, Alkaloids 4 Meda Polygonatum verticillatum Madhura Guru, Snigdha Madhura Shita Saponins, Polysaccharides 5 Vidari Pueraria tuberosa Madhura Guru, Snigdha Madhura Shita Isoflavonoids, Coumarins 6 Kakoli Lillium polyphyllum Madhura Guru, Snigdha Madhura Shita Alkaloids, Flavonoids 7 Kshira Kakoli Lillium sp. Madhura Guru, Snigdha Madhura Shita Glycosides, Saponins 8 Jivaka Microstylis wallichii Madhura Guru, Snigdha Madhura Shita Flavonoids, Sterols 9 Jivanti Leptadenia reticulata Madhura Guru, Snigdha Madhura Shita Leptadenosides, Alkaloids 10 Shalaparni Desmodium gangeticum Madhura, Tikta Guru, Snigdha Madhura Shita Isoflavones, Sterols Uses of Snehopaga Varga Dosha Karma (Effect on Doshas) How Snehopaga Varga Works Conclusion The Snehopaga Mahakashaya Varga plays a vital role in Ayurvedic Oleation Therapy (Snehana Karma) by enhancing the absorption and efficacy of medicated ghee and oils. These ten powerful herbs help in nourishment, rejuvenation, skin health, and nervous system balance, making them essential in Panchakarma and Rasayana therapies. 22. Swedopaga Mahakashaya Varga (Adjuvants of Sudation Therapy) Introduction The Swedopaga Mahakashaya Varga consists of ten medicinal plants that act as adjuvants to Swedana Karma (Sudation Therapy). These herbs enhance the therapeutic effect of Swedana, facilitating detoxification, sweat induction, and deep tissue relaxation. They help in balancing Vata and Kapha Dosha, reducing stiffness, pain, and swelling. List of Swedopaga Dravyas (Medicinal Plants of Swedopaga Varga) SI No Name Botanical Name Rasa (Taste) Guna (Properties) Vipaka (Post-digestive effect) Virya (Potency) Active Compounds 1 Shobhanjana Moringa oleifera Katu, Tikta Laghu, Ruksha Katu Ushna Moringinine, Flavonoids 2 Eranda Ricinus communis Madhura, Tikta Tikshna, Snigdha Madhura Ushna Ricinoleic Acid, Alkaloids 3 Arka Calotropis procera Katu Tikshna, Ruksha Katu Ushna Calotropin, Flavonoids 4 Vraschira Trianthema portulacastrum Katu, Tikta Laghu, Ruksha Katu Ushna Saponins, Alkaloids 5 Punarnava Boerhavia diffusa Tikta, Kashaya Laghu, Ruksha Madhura Ushna Boeravinone, Flavonoids 6 Yava Hordeum vulgare Madhura Laghu, Ruksha Madhura Shita Beta-glucans, Polyphenols 7 Tila Sesamum indicum Madhura, Kashaya Guru, Snigdha Madhura Ushna Sesamin, Tocopherols 8 Kulattha Dolichos biflorus Kashaya, Tikta Laghu, Ruksha Katu Ushna Polyphenols, Proteins 9 Masha Phaseolus mungo Madhura Guru, Snigdha Madhura Shita Lecithins, Flavonoids 10 Badara Ziziphus jujuba Madhura, Amla Guru, Snigdha Madhura Shita Triterpenoids, Flavonoids Uses of Swedopaga Varga Dosha Karma (Effect on Doshas) How Swedopaga Varga Works Conclusion The Swedopaga Mahakashaya Varga enhances the therapeutic effect of Swedana Karma by improving perspiration, circulation, and detoxification. These ten powerful herbs are essential for managing Vata and Kapha disorders, making them valuable in Panchakarma therapies. 23. Vamanopaga Mahakashaya Varga (Sub-emetics) Introduction The Vamanopaga Mahakashaya Varga consists of ten medicinal plants that act as adjuvants to Vamana Karma (Therapeutic Emesis). These herbs enhance the effectiveness of primary Vamana Dravyas, helping to expel excessive Kapha Dosha, toxins (Ama), and undigested food. They aid in conditions like chronic cough, asthma, indigestion, and skin diseases. List of Vamanopaga Dravyas (Medicinal Plants of Vamanopaga Varga) SI No Name Botanical Name Rasa (Taste) Guna (Properties) Vipaka (Post-digestive effect) Virya (Potency) Active Compounds 1 Madhu Honey Kashaya, Madhura Laghu, Ruksha Madhura Ushna Flavonoids, Enzymes 2 Madhuka Glycyrrhiza glabra Madhura, Tikta Guru, Snigdha Madhura Shita Glycyrrhizin, Saponins 3 Kovidara Bauhinia purpurea Kashaya Ruksha, Laghu Katu Shita Flavonoids, Tannins 4 Karbudara Bauhinia variegata Kashaya Ruksha, Laghu Katu Shita Phytosterols, Alkaloids 5 Nipa Anthocephalus cadamba Kashaya Ruksha, Laghu Katu Shita Terpenoids, Glycosides 6 Vidula Barringtonia acutangula Kashaya Ruksha, Tikshna Katu Shita Saponins, Tannins 7 Bimbi Coccinia indica Kashaya, Katu Ruksha, Laghu Katu Ushna Beta-carotene, Triterpenoids 8 Shanapushpi Crotalaria verrucosa Tikta, Katu Laghu, Tikshna Katu Ushna Alkaloids, Flavonoids 9 Sadapushpa Calotropis gigantea Tikta, Katu Tikshna, Sara Katu Ushna Calotropin, Glycosides 10 Pratyakpushpa Achyranthes aspera Katu, Tikta Laghu, Tikshna Katu Ushna Ecdysteroids, Saponins Uses of Vamanopaga Varga Dosha Karma (Effect on Doshas) How Vamanopaga Varga Works Conclusion The Vamanopaga Mahakashaya Varga strengthens Vamana Karma (therapeutic emesis) by aiding in Kapha elimination, detoxification, and respiratory health. These herbs are essential for managing chronic cough, skin disorders, indigestion, and metabolic imbalances, making them vital in Panchakarma therapies. 24. Virechanopaga Mahakashaya Varga (Sub-purgatives) Introduction The Virechanopaga Mahakashaya Varga includes ten medicinal plants that support Virechana Karma (therapeutic purgation). These herbs enhance the action of Virechana Dravyas like Trivrit (Operculina turpethum), helping in the elimination of excessive Pitta Dosha and toxins (Ama) from the intestines. They are beneficial in liver disorders, skin diseases, chronic constipation, and metabolic imbalances. List of Virechanopaga Dravyas (Medicinal Plants of Virechanopaga Varga) SI No Name Botanical Name Rasa (Taste) Guna (Properties) Vipaka (Post-digestive effect) Virya (Potency) Active Compounds 1 Draksha Vitis vinifera Madhura Guru, Snigdha Madhura Shita Resveratrol, Flavonoids 2 Kashmarya Gmelina arborea Madhura, Katu Laghu, Ruksha Ushna Ushna Lignans, Alkaloids 3 Parushaka Grewia asiatica Madhura Guru, Snigdha Madhura Shita Anthocyanins, Polyphenols 4 Abhaya Terminalia chebula Madhura, Kashaya Laghu, Ruksha Ushna Ushna Tannins, Gallic acid 5 Amalaka Emblica officinalis Pancharasa (except Lavana) Ruksha, Laghu Madhura Shita Vitamin C, Phyllembelic acid 6 Vibhitaka Terminalia bellirica Kashaya Ruksha, Laghu Madhura Ushna Tannins, Beta-sitosterol 7 Kuvala Zizyphus sativa Madhura, Kashaya Picchila, Guru Madhura Shita Saponins, Flavonoids 8 Badara Zizyphus mauritiana Madhura, Amla, Kashaya Picchila, Guru Madhura Shita Vitamin C, Polyphenols 9 Karkandhu Zizyphus nummularia Madhura, Kashaya Picchila, Guru Madhura Shita Triterpenoids, Alkaloids 10 Pilu Salvadora persica Madhura, Amla, Kashaya, Tikta Laghu, Snigdha Katu Ushna Alkaloids, Glucosinolates Uses of Virechanopaga Varga Dosha Karma (Effect on Doshas) How Virechanopaga Varga Works Conclusion The Virechanopaga Mahakashaya Varga is essential for Virechana Karma (purgation therapy). It plays a vital role in detoxification,

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Pharmacological Insights into Charakokta Dashemani: Karmas, Rasa, Guna, Vipaka, Veerya, Dosha Karma, and Therapeutic Potential Part -2 (11- 20 Dashemani Mahakashaya)

11. Traptighna Maha Kashaya Varga (Digestants) Traptighna refers to substances that alleviate excessive satiety (Tripti) and improve digestion. These herbs are particularly beneficial when a person experiences a loss of appetite or reluctance to eat due to sluggish digestion and Kapha-related disorders. According to Charaka Samhita, ten key herbs fall under this category, possessing properties that stimulate Agni (digestive fire) and aid digestion. “Nagarachavyachitrakavidangamurvaguduchivachamustapippalipatolānīti dashemāni traptighnāni bhavanti.” (Ch. Su. 4/8) List of Traptighna Herbs No. Herb (Botanical Name) Taste (Rasa) Properties (Guna) Post-Digestive Effect (Vipaka) Potency (Virya) Active Compounds 1. Nagara (Zingiber officinale) Pungent (Katu) Light (Laghu), Dry (Ruksha) Sweet (Madhura) Hot (Ushna) Gingerol, Shogaol, Zingiberene 2. Chavya (Piper chaba) Pungent (Katu) Sharp (Tikshna), Dry (Ruksha) Pungent (Katu) Hot (Ushna) Piperine, Chavicine 3. Chitraka (Plumbago zeylanica) Pungent (Katu) Sharp (Tikshna), Light (Laghu), Dry (Ruksha) Pungent (Katu) Hot (Ushna) Plumbagin, Flavonoids 4. Vidanga (Embelia ribes) Pungent (Katu), Astringent (Kashaya) Light (Laghu), Dry (Ruksha) Pungent (Katu) Hot (Ushna) Embelin, Tannins, Quercetin 5. Murva (Marsedenia tenacissima) Bitter (Tikta) Heavy (Guru), Dry (Ruksha) Pungent (Katu) Hot (Ushna) Alkaloids, Glycosides 6. Guduchi (Tinospora cordifolia) Bitter (Tikta), Astringent (Kashaya) Heavy (Guru), Oily (Snigdha) Sweet (Madhura) Hot (Ushna) Berberine, Tinosporin, Alkaloids 7. Vacha (Acorus calamus) Bitter (Tikta), Pungent (Katu) Light (Laghu), Sharp (Tikshna) Pungent (Katu) Hot (Ushna) β-Asarone, Eugenol, Tannins 8. Musta (Cyperus rotundus) Pungent (Katu), Bitter (Tikta) Light (Laghu), Dry (Ruksha) Pungent (Katu) Cold (Shita) Cyperene, Sesquiterpenes, Flavonoids 9. Pippali (Piper longum) Pungent (Katu), Sweet (Madhura) Light (Laghu), Oily (Snigdha) Sweet (Madhura) Mildly Hot (Anushna) Piperine, Myristicin, Lignans 10. Patola (Trichosanthes dioica) Bitter (Tikta) Light (Laghu), Oily (Snigdha) Pungent (Katu) Hot (Ushna) Cucurbitacins, Flavonoids Applications: The Traptighna herbs are useful in conditions where a person experiences loss of appetite (Aruchi) and reluctance to eat due to heaviness in the stomach. These herbs work by improving digestive fire (Agni), reducing excess mucus (Kapha), and alleviating symptoms of indigestion, bloating, and sluggish digestion. 12. Arshoghna Mahakashaya Varga (Anti-Hemorrhoidal Herbs) Arshoghna refers to herbs that help in the treatment of Arshas (piles/hemorrhoids). These herbs possess properties that reduce swelling, pacify aggravated Vata and Kapha, promote digestion, and help in healing the affected area. According to Charaka Samhita, ten key herbs are categorized under this group. “Bilvachitrakanāgarātiviṣābhayādhanvayāsakadāruharidrāvachāchavyānīti daśemāni arshoghnāni bhavanti.” (Ch. Su. 4/11) List of Arshoghna Herbs No. Herb (Botanical Name) Taste (Rasa) Properties (Guna) Post-Digestive Effect (Vipaka) Potency (Virya) Active Compounds 1. Kutaja (Holarrhena antidysenterica) Bitter (Tikta), Astringent (Kashaya) Light (Laghu), Dry (Ruksha) Pungent (Katu) Cold (Shita) Conessine, Alkaloids 2. Bilwa (Aegle marmelos) Astringent (Kashaya), Bitter (Tikta) Light (Laghu), Dry (Ruksha) Pungent (Katu) Hot (Ushna) Marmelosin, Tannins, Flavonoids 3. Chitraka (Plumbago zeylanica) Pungent (Katu) Sharp (Tikshna), Dry (Ruksha), Light (Laghu) Pungent (Katu) Hot (Ushna) Plumbagin, Glycosides 4. Nagara (Zingiber officinale) Pungent (Katu) Sharp (Tikshna), Dry (Ruksha), Light (Laghu) Pungent (Katu) Hot (Ushna) Gingerol, Shogaol, Zingiberene 5. Ativisha (Aconitum heterophyllum) Bitter (Tikta), Pungent (Katu) Light (Laghu), Dry (Ruksha), Sharp (Tikshna) Sweet (Madhura) Hot (Ushna) Aconitine, Alkaloids 6. Abhaya (Terminalia chebula) Astringent (Kashaya), Bitter (Tikta) Light (Laghu), Dry (Ruksha) Sweet (Madhura) Hot (Ushna) Chebulinic acid, Tannins 7. Dhanvayasaka (Fagonia critica) Bitter (Tikta) Light (Laghu), Oily (Snigdha) Sweet (Madhura) Cold (Shita) Saponins, Flavonoids 8. Daruharidra (Berberis aristata) Astringent (Kashaya), Bitter (Tikta) Dry (Ruksha), Light (Laghu) Pungent (Katu) Hot (Ushna) Berberine, Alkaloids 9. Vacha (Acorus calamus) Pungent (Katu), Bitter (Tikta) Light (Laghu), Sharp (Tikshna) Pungent (Katu) Hot (Ushna) β-Asarone, Eugenol 10. Chavya (Piper chaba) Pungent (Katu) Sharp (Tikshna), Light (Laghu), Dry (Ruksha) Pungent (Katu) Hot (Ushna) Piperine, Chavicine Applications: These herbs are useful in both dry piles (Shushka Arshas) and bleeding hemorrhoids (Rakta Arshas). They work by: 13. Kushthaghna Mahakashaya Varga (Anti-Dermatosis Herbs) Kushthaghna refers to herbs that help in treating Kushtha (skin diseases), including leprosy, eczema, psoriasis, fungal infections, and other dermatological disorders. These herbs possess antimicrobial, blood-purifying, and skin-rejuvenating properties. According to Charaka Samhita, ten key herbs are classified under this category. “Khadirābhayāmalakaharidrāruṣkarasaptaparṇāragvadhakaravīraviḍaṅgajātīpravālā iti daśemāni kuṣṭhaghna bhavanti.” (Ch. Su. 4/11) List of Kushthaghna Herbs No. Herb (Botanical Name) Taste (Rasa) Properties (Guna) Post-Digestive Effect (Vipaka) Potency (Virya) Active Compounds 1. Khadira (Acacia catechu) Bitter (Tikta), Astringent (Kashaya) Light (Laghu), Dry (Ruksha) Pungent (Katu) Cold (Shita) Catechin, Tannins 2. Abhaya (Terminalia chebula) Astringent (Kashaya), Bitter (Tikta) Light (Laghu), Dry (Ruksha) Sweet (Madhura) Hot (Ushna) Chebulinic acid, Tannins 3. Amalaka (Phyllanthus emblica) Astringent (Kashaya), Sour (Amla) Light (Laghu), Dry (Ruksha) Sweet (Madhura) Cold (Shita) Vitamin C, Gallic acid 4. Haridra (Curcuma longa) Bitter (Tikta), Pungent (Katu) Light (Laghu), Dry (Ruksha) Pungent (Katu) Hot (Ushna) Curcumin, Tumerone 5. Arushkara (Semecarpus anacardium) Bitter (Tikta), Astringent (Kashaya) Light (Laghu), Oily (Snigdha) Pungent (Katu) Hot (Ushna) Bhilawanol, Anacardic acid 6. Saptaparna (Alstonia scholaris) Bitter (Tikta), Pungent (Katu) Light (Laghu), Oily (Snigdha) Pungent (Katu) Hot (Ushna) Alkaloids, Echitamine 7. Aragwadha (Cassia fistula) Sweet (Madhura) Heavy (Guru), Oily (Snigdha) Sweet (Madhura) Cold (Shita) Anthraquinones, Flavonoids 8. Karavira (Nerium odorum) Bitter (Tikta), Pungent (Katu) Light (Laghu), Dry (Ruksha) Pungent (Katu) Hot (Ushna) Oleandrin, Glycosides 9. Vidanga (Embelia ribes) Bitter (Tikta), Pungent (Katu) Light (Laghu), Dry (Ruksha) Pungent (Katu) Hot (Ushna) Embelin, Tannins 10. Jatipravala (Jasminum officinale) Bitter (Tikta), Astringent (Kashaya) Light (Laghu), Oily (Snigdha) Pungent (Katu) Hot (Ushna) Flavonoids, Alkaloids Applications: These herbs are beneficial in treating various skin disorders (Kushtha Roga) by: 14. Kandughna Mahakashaya Varga (Anti-Pruritic Herbs) Kandughna refers to herbs that help in treating Kandu (itching, pruritus) and related skin conditions such as eczema, dermatitis, allergies, and fungal infections. These herbs possess antimicrobial, anti-inflammatory, and blood-purifying properties that help soothe irritated skin. According to Charaka Samhita, ten key herbs are classified under this category. “Chandananaladakratamālanaktamālanimbakuṭajasarṣapamadhukadāruharidrāmastānīti daśemāni kaṇḍūghnāni bhavanti.” (Ch. Su. 4/11) List of Kandughna Herbs No. Herb (Botanical Name) Taste (Rasa) Properties (Guna) Post-Digestive Effect (Vipaka) Potency (Virya) Active Compounds 1. Chandana (Santalum album) Bitter (Tikta), Sweet (Madhura) Light (Laghu), Dry (Ruksha) Pungent (Katu) Cold (Shita) Santalol, α-Santalene 2. Nalada (Nardostachys jatamansi) Bitter (Tikta), Astringent (Kashaya) Light (Laghu), Oily (Snigdha) Pungent (Katu) Cold (Shita) Jatamansone, Alkaloids 3. Kratamala (Cassia fistula) Sweet (Madhura) Heavy (Guru), Oily (Snigdha) Sweet (Madhura) Cold (Shita) Anthraquinones, Flavonoids 4. Naktamala (Pongamia pinnata)

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Pharmacological Insights into Charakokta Dashemani: Karmas, Rasa, Guna, Vipaka, Veerya, Dosha Karma, and Therapeutic Potential Part -1 (1- 10 Dashemani Mahakashaya)

1. Jivaniya Mahakashaya (Vitalizers) in Ayurveda Jivaniya Mahakashaya, as described in Charaka Samhita (Ch. Su. 4/8), consists of medicinal plants known for their life-sustaining, rejuvenating, and tissue-nourishing properties. These herbs help maintain Sapta Dhatus (seven body tissues), enhance vitality, and promote longevity. जीवनीय (जीवन) – जीवनम् आयुः तस्मै हितं जीवनीयम् । जीवनीयशब्देनेहायुष्यत्वमभिप्रेतम्। (चक्रपाणि च. सू. 4/8) जीवनीयं प्राणानां संधारकम् । (इन्दु on अ. सं. सू. 34) According to Chakrapani, “Jivaniya” refers to substances that are beneficial for life extension. Indu further states that Jivaniya Dravyas sustain Prana (life force), supporting overall health and well-being. Table: Jivaniya Mahakashaya – Ayurvedic & Pharmacological Profile SI No. Dravya (Herb) Botanical Name Rasa (Taste) Guna (Property) Vipaka (Post-digestive effect) Virya (Potency) Active Compounds 1 Jivaka Microstylis wallichii Madhura Guru, Snigdha Madhura Shita Alkaloids, Saponins, Flavonoids 2 Rishabhaka Microstylis mucifera Madhura Guru, Snigdha Madhura Shita Glycosides, Phenols 3 Meda Polygonatum cirrhifolium Madhura Guru, Snigdha Madhura Shita Steroidal Saponins, Flavonoids 4 Mahameda Polygonatum verticillatum Madhura Guru, Snigdha Madhura Shita Alkaloids, Tannins 5 Kakoli Fritillaria roylei Madhura Guru, Snigdha Madhura Shita Steroidal Saponins, Mucilage 6 Kshira Kakoli Lilium polyphyllum Madhura Guru, Snigdha Madhura Shita Glycosides, Flavonoids 7 Mashaparni Teramnus labialis Madhura Guru, Snigdha Madhura Shita Proteins, Amino Acids 8 Jivanti Leptadenia reticulata Madhura Guru, Snigdha Madhura Shita Leptadenosides, Alkaloids 9. Mudgaparni Phaseolus trilobus Madhura Guru, Snigdha Madhura Shita – 10. Madhuka Glycyrrhiza glabra Madhura Guru, Snigdha Madhura Shita – Therapeutic Applications The plants in Jivaniya Mahakashaya play a vital role in: Conclusion Jivaniya Mahakashaya consists of herbs that are highly valued in Ayurveda for their rejuvenating and strengthening effects. These plants contribute to health maintenance, disease prevention, and overall vitality, making them essential components of Ayurvedic therapeutics. 2. Brahmaniya Mahakashaya (Nourishing Herbs) in Ayurveda Brahmaniya Mahakashaya, as described in Charaka Samhita (Ch. Su. 4/9), consists of medicinal plants known for their nourishing, strengthening, and bulk-promoting properties. These herbs are particularly beneficial for individuals with Krisha (lean body constitution), helping in muscle growth, tissue development, and overall nourishment. According to Ayurveda, Brahmaniya Dravyas promote Dhatu Pushti (tissue nourishment) and enhance body strength by providing essential nutrients and supporting metabolism. Table: Brahmaniya Mahakashaya – Ayurvedic & Pharmacological Profile SI No. Dravya (Herb) Botanical Name Rasa (Taste) Guna (Property) Vipaka (Post-digestive effect) Virya (Potency) Active Compounds 1 Kshirini Euphorbia hirta Tikta, Katu Laghu Madhura Ushna Alkaloids, Flavonoids 2 Rajakshavaka Euphorbia microphylla Tikta Laghu Madhura Ushna Tannins, Glycosides 3 Ashwagandha Withania somnifera Tikta, Katu, Madhura Laghu, Snigdha Madhura Ushna Withanolides, Alkaloids 4 Kakoli Fritillaria roylei Madhura Guru, Snigdha Madhura Shita Steroidal Saponins, Mucilage 5 Kshira Kakoli Lilium polyphyllum Madhura Guru, Snigdha Madhura Shita Glycosides, Flavonoids 6 Vatyayani Sida cordifolia Madhura Guru, Snigdha Madhura Shita Alkaloids, Ephedrine 7 Bhadraudani Sida veronicaefolia Madhura Guru, Snigdha Madhura Shita Phenolic compounds 8 Bharadwaji Thespesia lampas Madhura Guru, Snigdha Madhura Shita Flavonoids, Tannins 9 Payasya Pueraria tuberosa Madhura Guru, Snigdha Madhura Shita Isoflavones, Tuberins 10 Rushyagandha Argyreia speciosa Madhura, Katu, Tikta Laghu, Snigdha Madhura Ushna Alkaloids, Steroids Therapeutic Applications The herbs in Brahmaniya Mahakashaya play a significant role in: Conclusion Brahmaniya Mahakashaya includes herbs that promote nourishment, enhance body strength, and help in weight gain. These plants are particularly beneficial for individuals suffering from malnutrition, debility, and excessive weight loss, making them a vital part of Ayurvedic therapeutics. 3. Lekhaniya Mahakashaya (Emaciating Herbs) in Ayurveda Lekhaniya Mahakashaya, as described in Charaka Samhita (Ch. Su. 4/10), consists of medicinal plants known for their Lekhana (scraping) and Karshana (emaciating) properties. These herbs help in removing excess Meda Dhatu (fat tissue), clearing obstructed channels (Srotoshodhana), and managing obesity (Sthoulya Chikitsa). According to Yogendranath Sen, “Lekhana” refers to substances that cause depletion (Karshana), reducing excess fat and Kapha accumulation. Indu further states that Lekhaniya Dravyas help remove pathological deposits from the body. Table: Lekhaniya Mahakashaya – Ayurvedic & Pharmacological Profile SI No. Dravya (Herb) Botanical Name Rasa (Taste) Guna (Property) Vipaka (Post-digestive effect) Virya (Potency) Active Compounds 1 Musta Cyperus rotundus Tikta, Kashaya Laghu, Ruksha Katu Shita Flavonoids, Essential Oils 2 Kushtha Saussurea lappa Tikta, Katu Laghu, Ruksha Katu Ushna Sesquiterpenes, Alkaloids 3 Haridra Curcuma longa Tikta, Katu Ruksha, Laghu Katu Ushna Curcuminoids, Volatile Oils 4 Daruharidra Berberis aristata Tikta, Katu Ruksha, Laghu Katu Ushna Berberine, Alkaloids 5 Vacha Acorus calamus Tikta, Katu Laghu, Tikshna Katu Ushna Beta-asarone, Flavonoids 6 Ativisha Aconitum heterophyllum Tikta, Katu Laghu, Ruksha Katu Ushna Alkaloids, Diterpenoids 7 Chitraka Plumbago zeylanica Katu, Tikta Laghu, Tikshna Katu Ushna Plumbagin, Tannins 8 Katurohini Picrorhiza kurroa Tikta, Katu Laghu, Ruksha Katu Ushna Kutkin, Glycosides 9 Chirabilva Holoptelia integrifolia Tikta Ruksha, Laghu Katu Ushna Tannins, Alkaloids 10 Haimavathi Iris germanica Katu, Tikta Laghu, Tikshna Katu Ushna Flavonoids, Saponins Therapeutic Applications The herbs in Lekhaniya Mahakashaya are widely used for: Conclusion Lekhaniya Mahakashaya includes herbs that are highly effective in obesity management, detoxification, and improving metabolism. These plants play a significant role in Ayurvedic weight management, lipid metabolism regulation, and prevention of lifestyle disorders. 4. Bhedaniya Mahakashaya (Purgative Herbs) in Ayurveda Bhedaniya Mahakashaya, as described in Charaka Samhita (Ch. Su. 4/9), consists of medicinal plants known for their Bhedana (purgative) and Malashodhana (cleansing) properties. These herbs help in removing vitiated Doshas and accumulated waste (Mala) from the body, making them beneficial in conditions like Vibandha (constipation), Pitta-Kapha disorders, and detoxification therapies such as Virechana (therapeutic purgation). According to Ayurveda, Bhedaniya Dravyas stimulate bowel movements, clear intestinal toxins, and regulate digestion, thus supporting gut health and metabolic balance. Table: Bhedaniya Mahakashaya – Ayurvedic & Pharmacological Profile SI No. Dravya (Herb) Botanical Name Rasa (Taste) Guna (Property) Vipaka (Post-digestive effect) Virya (Potency) Active Compounds 1 Suvaha Operculina turpethum Katu, Tikta Laghu, Ruksha Katu Ushna Glycosides, Resins 2 Urubaka Calotropis procera Katu, Tikta Laghu, Tikshna Katu Ushna Cardiac Glycosides, Alkaloids 3 Eranda Ricinus communis Katu, Madhura Snigdha, Tikshna Madhura Ushna Ricin, Fatty Acids 4 Agnimukhi Gloriosa superba Tikta, Katu Laghu, Tikshna Katu Ushna Colchicine, Alkaloids 5 Chitraka Plumbago zeylanica Katu, Tikta Tikshna, Ruksha Katu Ushna Plumbagin, Flavonoids 6 Chirabilva Holoptelia integrifolia Tikta, Kashaya Laghu, Ruksha Katu Ushna Tannins, Saponins 7 Shankhini Euphorbia dracunculoides

Internal structure of kidney globeayush.com
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Over view : Internal Structure of Kidney

Introduction : Excretory system plays an important role in body balance by eliminating all the wastes that are released after metabolic process which are toxic to the body and disturb body homeostasis which leads to various diseases . Kidneys, the main organs which play crucial role in this eliminating process. Internal structure of Kidney : Kidneys are a pair of bean shaped of organs , plays crucial role in filtering waste products from blood, maintain electrolyte balance . Internal structure of kidney [Frontal section of kidney ] shows two primary regions : RENAL CORTEX : This is the outer region of kidney which contain renal corpuscles and portions of renal tubules . The portion of cortex which extends in between the medullary pyramids are called as columns of bertin or renal columns. RENAL MEDULLA : Inner region , this part is organized into pyramid shaped structures called renal pyramids Base of pyramid faces cortex and apex known as renal papilla pointed towards the renal pelvis . Collecting System : It includes renal calyces which play role in collection and transportation of urine . These calyces are divided into major and minor calyces . In each kidney there are 8 to 12 minor calyces and they merge and form 2 to 3 major calyces these major calyces further fused and form the renal pelvis which is funnel shaped leads urine into ureter and than finally into urinary bladder. Functional Unit Of Kidney : Nephron : Nephron : It is the structural and functional unit of kidney , there are about 1 to 1.3 million nephrons are present in each kidney . STRUCTURE OF NEPHRON : There are two parts of kidney they are : Renal corpuscle [Malpighian Tubule] Glomerular capillaries and bowman’s capsule together called as Malpighian tubule or Renal corpuscle. Glomerulus : These glomerular capillaries are purely arterial . Afferent arteriole enters into bowman’s capsule and form tuft of capillaries to form anastomosis of glomerulus and leaves as the efferent arteriole. The glomerulus is made up of endothelial cells and these cells arranged in a intricate manner so they form pores called as Fenestrae or filtration pores through which the materials get filtered from blood and these fenestrae has the diameter of 0.1micron . NOTE : The diameter of afferent arteriole is greater than the efferent arteriole . Bowman’s capsule : This is a cup shaped structure which consists of two layers , outer parietal layer and inner visceral layer . The inner visceral layer continues as the parietal layer and this parietal layer continues as the tubular portion of nephron .The space between the visceral and parietal layer is continued as the lumen of the tubular portion . The basement membrane of the bowman’s capsule has slit pores, which are helpful in filtration . This bowman’s capsule is made up of single layer of epithelial cells resting on basement membrane. The basement membrane of glomerular capillaries and Basement membrane of visceral layer together form filtering membrane . Note : The fusion between epithelium and basement membrane is not complete , these epithelial cells show some cytoplasmic extensions , these extensions are called as pedicels [feet] and the epithelial cells with these extensions are called as podocytes . These cells form slit pores helpful in filtration. Tubular Portion Of Nephron : This portion of nephron is divided into : PROXIMAL CONVOLUTED TUBULE : LOOP OF HENEL : DISTAL CONVOLUTED TUBULE : COLLECTING DUCT : DCT enters into collecting duct , in this 7 to 8 collecting ducts unite and form a straight collecting duct Juxta glomerular apparatus [JGA]: These are specialized structures in kidney located near glomerulus ,plays crucial role in regulating blood pressure and glomerular filtration rate by sensing and responding to changes in blood flow and sodium and chloride levels . Release hormone called as renin [ peptide made up of 340 amino acids] MACULA DENSA : LOCATION : It is located at the terminal end portion of thick ascending segment of loop of Henle before it enters into distal convoluted tubule between the efferent arteriole and afferent arteriole of same nephron. It is close to afferent arteriole . FUNCTION : Tubulo glomerular feed back mechanism and Thromboxane A2 secretion . EXTRA GLOMERULAR MESENGIAL CELLS : LOCATION : Located in triangular area between Afferent arteriole ,Efferent arteriole and Macula densa. These cells are also called as angular cells, Lacis cells, polkissen cells or goormaghtigh cells . These cells also present inside glomerular interstitial matrix there, these cells are called as Glomerular mesangial cells . FUNCTION : Release prostaglandins and cytokines where as, the Glomerular mesangial cells plays crucial role in phagocytic action and regulate glomerular filtration by contractile property . JUXTA GLOMERULAR CELLS OR GRANULAR CELLS : LOCATION : These are smooth muscle cells in afferent arteriole wall just before it entry to bowman’s capsule . Between bowman’s capsule layers and tunica media and tunica adventia of afferent arteriole . These cells form polar cushion. Conclusion : The internal structure of the kidney is a marvel of biological engineering, designed to efficiently filter blood, remove waste, and maintain the body’s fluid and electrolyte balance. Comprising the cortex, medulla, and pelvis, each component plays a crucial role in the kidney’s function. The nephrons, as the kidney’s functional units, execute the complex processes of filtration, reabsorption, and secretion, ensuring the body’s homeostasis is preserved. Understanding the intricate architecture of the kidney not only highlights its vital role in health but also underscores the importance of maintaining renal health through proper lifestyle choices and medical care. As research continues to unfold, the kidney’s structure serves as a foundation for advancements in treating renal diseases and enhancing overall well-being. References Reputable Sources on Kidney Anatomy and Physiology 1. Kidney Anatomy – Medscape Reference An overview of kidney anatomy, including gross anatomy and anatomical relationships.Read more 2. Gross Anatomy of the Kidney – Lumen Learning A detailed look at the kidney’s gross anatomical structures.Read more 3. Anatomy, Abdomen and Pelvis: Kidneys –

Ayurvedic drugs globeayush.com
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100+ AYURVEDIC DRUGS ACCORDING TO BAMS NCISM SYLLABUS

Here is the combined table with all the Ayurvedic herbs you listed, including their botanical names and families: Botanical names and Family Sanskrit Name Botanical Name Family Agnimantha Clerodendrum phlomidis Lamiaceae Ahiphena Papaver somniferum Papaveraceae Ajamoda Apium graveolens Apiaceae Amalaki Emblica officinalis Phyllanthaceae Apamarga Achyranthes aspera Amaranthaceae Aragwadha Cassia fistula Fabaceae Arjuna Terminalia arjuna Combretaceae Ashoka Saraca asoca Fabaceae Ashwagandha Withania somnifera Solanaceae Asthishrunkhala Cissus quadrangularis Vitaceae Ativisha Aconitum heterophyllum Ranunculaceae Bakuchi Psoralea corylifolia Fabaceae Bala Sida cordifolia Malvaceae Bhallataka Semecarpus anacardium Anacardiaceae Dhanyaka Coriandrum sativum Apiaceae Beejaka Pterocarpus marsupium Fabaceae Bharangi Clerodendrum serratum Lamiaceae Bhrungaraja Eclipta alba (E. prostrata) Asteraceae Bhumyamalaki Phyllanthus amarus Phyllanthaceae Bilva Aegle marmelos Rutaceae Brahmi Bacopa monnieri Plantaginaceae Bruhati Solanum indicum Solanaceae Chakramarda Cassia tora Fabaceae Chandana Santalum album Santalaceae Chitraka Plumbago zeylanica Plumbaginaceae Dadima Punica granatum Lythraceae Dhataki Woodfordia fruticosa Lythraceae Dhanvayasa Fagonia cretica Zygophyllaceae Ela Elettaria cardamomum Zingiberaceae Eranda Ricinus communis Euphorbiaceae Gambhari Gmelina arborea Lamiaceae Gokshura Tribulus terrestris Zygophyllaceae Guduchi Tinospora cordifolia Menispermaceae Guggulu Commiphora mukul Burseraceae Haridra Curcuma longa Zingiberaceae Haritaki Terminalia chebula Combretaceae Hingu Ferula narthex Apiaceae Jambu Syzygium cumini Myrtaceae Japa Hibiscus rosa-sinensis Malvaceae Jatamansi Nardostachys grandiflora (N. jatamansi) Caprifoliaceae Jeeraka Cuminum cyminum Apiaceae Jyotishmati Celastrus paniculatus Celastraceae Kalamegha Andrographis paniculata Acanthaceae Jatiphala Myristica fragrans Myristicaceae Kampillaka Mallotus philippensis Euphorbiaceae Kanchanara Bauhinia variegata Fabaceae Sarpagandha Rauvolfia serpentina Apocynaceae Kantakari Solanum xanthocarpum (S. surattense) Solanaceae Kapikachhu Mucuna pruriens Fabaceae Karkatshrungi Pistacia integerrima Anacardiaceae Katuki Picrorhiza kurroa Plantaginaceae Khadira Acacia catechu Fabaceae Kumari Aloe vera Asphodelaceae Kumkuma Crocus sativus Iridaceae Kutaja Holarrhena pubescens Apocynaceae Lajjalu Mimosa pudica Fabaceae Lavanga Syzygium aromaticum Myrtaceae Lodhra Symplocos racemosa Symplocaceae Mandukaparni Centella asiatica Apiaceae Maricha Piper nigrum Piperaceae Meshashrungi Gymnema sylvestre Apocynaceae Musta Cyperus rotundus Cyperaceae Nagkeshara Mesua ferrea Calophyllaceae Nimba Azadirachta indica Meliaceae Nirgundi Vitex negundo Lamiaceae Pashanabheda Bergenia ciliata Saxifragaceae Patha Cissampelos pareira Menispermaceae Pippali Piper longum Piperaceae Punarnava Boerhavia diffusa Nyctaginaceae Rasna Pluchea lanceolata Asteraceae Rasona Allium sativum Amaryllidaceae Sariva Hemidesmus indicus Apocynaceae Shallaki Boswellia serrata Burseraceae Vacha Acorus calamus Acoraceae Shalmali Bombax ceiba Malvaceae Shankhapushpi Convolvulus pluricaulis Convolvulaceae Shatavari Asparagus racemosus Asparagaceae Shigru Moringa oleifera Moringaceae Twak Cinnamomum aromaticum Lauraceae Usheera Vetiveria zizanioides Poaceae Varuna Crataeva magna Capparaceae Vasa Justicia adhatoda Acanthaceae Vatsanabha Aconitum ferox Ranunculaceae Vibhitaki Terminalia bellirica Combretaceae Vidanga Embelia ribes Primulaceae Yashtimadhu Glycyrrhiza glabra Fabaceae Family-Wise of Ayurvedic Herbs Family Number of Drugs Drugs Fabaceae 10 Aragwadha, Bakuchi, Beejaka, Chakramarda, Dhanyaka, Haritaki, Jatiphala, Khadira, Kantakari, Vatsanabha Lamiaceae 6 Agnimantha, Bharangi, Gambhari, Jyotishmati, Nirgundi, Tulasi Zingiberaceae 4 Ela, Haridra, Shunthi, Talisapatra Apiaceae 4 Ajamoda, Dhanyaka, Jeeraka, Mandukaparni Combretaceae 3 Arjuna, Haritaki, Vibhitaki Apocynaceae 4 Kutaja, Meshashrungi, Sariva, Sarpagandha Asteraceae 3 Bhrungaraja, Rasna, Chakramarda Poaceae 2 Usheera, Vetiveria zizanioides Phyllanthaceae 2 Amalaki, Bhumyamalaki Solanaceae 3 Ashwagandha, Bruhati, Kantakari Meliaceae 2 Jambu, Nimba Burseraceae 2 Guggulu, Shallaki Rutaceae 2 Bilva, Jatamansi Malvaceae 3 Bala, Shalmali, Japa Menispermaceae 2 Guduchi, Patha Ranunculaceae 2 Ativisha, Vatsanabha Primulaceae 2 Vidanga, Embelia ribes Moringaceae 1 Shigru Asparagaceae 1 Shatavari Lauraceae 1 Twak Iridaceae 1 Kumkuma Euphorbiaceae 1 Eranda Celastraceae 1 Jyotishmati Pinaceae 1 Talisapatra Capparaceae 1 Varuna Myrtaceae 1 Lavanga Acanthaceae 1 Vasa Amaranthaceae 1 Apamarga Asphodelaceae 1 Kumari Zygophyllaceae 1 Gokshura Nyctaginaceae 1 Punarnava Santalaceae 1 Chandana Plumbaginaceae 1 Chitraka Saxifragaceae 1 Pashanabheda Vitaceae 1 Asthishrunkhala Cypereaceae 1 Musta Rosaceae 1 Lodhra Anacardiaceae 1 Bhallataka Symplocaceae 1 Lodhra Acoraceae 1 Vacha Summary Family-wise Karma and Modern Pharmacological Effects of Ayurvedic Herbs Family Ayurvedic Karma (Traditional Effects) Modern Pharmacological Effects Fabaceae Laxative, Blood purifier, Antimicrobial, Detoxifier Antioxidant, Hepatoprotective, Anti-inflammatory, Antidiabetic Lamiaceae Anti-inflammatory, Neuroprotective, Immunomodulator CNS stimulant, Antiviral, Analgesic, Antimicrobial Zingiberaceae Digestive stimulant, Carminative, Anti-inflammatory Gastroprotective, Anti-nausea, Anti-inflammatory, Antioxidant Apiaceae Carminative, Antispasmodic, Memory enhancer Digestive tonic, Antiflatulent, Hepatoprotective, Cognitive enhancer Combretaceae Cardioprotective, Rejuvenative, Laxative Hypolipidemic, Antioxidant, Cardiotonic Apocynaceae Antidiabetic, Blood purifier, Antihypertensive Hypoglycemic, Antihypertensive, Antimicrobial Asteraceae Hair growth promoter, Anti-inflammatory, Vata-pacifying Hepatoprotective, Wound healing, Antioxidant Poaceae Cooling, Diuretic, Pitta-pacifying Antipyretic, Diuretic, Antioxidant Phyllanthaceae Rejuvenative, Liver tonic, Immunomodulator Hepatoprotective, Antiviral, Anti-inflammatory Solanaceae Adaptogenic, Strength promoter, Expectorant Anxiolytic, Anti-stress, Anti-asthmatic Meliaceae Antidiabetic, Blood purifier, Antimicrobial Antifungal, Antibacterial, Antidiabetic Burseraceae Anti-inflammatory, Joint pain reliever, Lipid-lowering Anti-arthritic, Hypolipidemic, Antioxidant Rutaceae Nervine tonic, Digestive stimulant, Memory booster Neuroprotective, Antispasmodic, Gastroprotective Malvaceae Strength promoter, Rejuvenative, Cooling Anti-inflammatory, Muscle relaxant, Antioxidant Menispermaceae Immunomodulator, Antipyretic, Anti-inflammatory Immunostimulant, Antipyretic, Anti-cancer Ranunculaceae Digestive stimulant, Detoxifier, Antipyretic Antipyretic, Anti-inflammatory, Neuroprotective Primulaceae Anthelmintic, Digestive stimulant, Blood purifier Antiparasitic, Hepatoprotective, Antioxidant Moringaceae Anti-inflammatory, Nutrient-rich, Antioxidant Anticancer, Anti-inflammatory, Nutrient-dense Asparagaceae Rejuvenative, Female tonic, Cooling Estrogenic, Reproductive health booster, Antioxidant Lauraceae Carminative, Digestive, Warming Antimicrobial, Anti-inflammatory, Digestive stimulant Iridaceae Blood purifier, Skin glow enhancer, Mood stabilizer Antidepressant, Skin tonic, Anti-inflammatory Euphorbiaceae Laxative, Anti-inflammatory, Vata-pacifying Laxative, Anti-inflammatory, Antispasmodic Celastraceae Memory booster, Nervine tonic Cognitive enhancer, Neuroprotective, Antioxidant Pinaceae Expectorant, Antimicrobial Antibacterial, Respiratory tonic, Anti-inflammatory Capparaceae Diuretic, Stone dissolver Nephroprotective, Antilithic (Kidney stone dissolver) Myrtaceae Antimicrobial, Digestive stimulant Antibacterial, Antifungal, Gastroprotective Acanthaceae Expectorant, Cough suppressant Bronchodilator, Antitussive, Anti-asthmatic Amaranthaceae Detoxifier, Laxative, Kaphahara Anti-inflammatory, Antioxidant, Hepatoprotective Asphodelaceae Skin healer, Digestive, Liver tonic Hepatoprotective, Wound healer, Antioxidant Zygophyllaceae Diuretic, Aphrodisiac, Kidney tonic Nephroprotective, Libido-enhancing, Anti-inflammatory Nyctaginaceae Diuretic, Swelling reducer, Liver protector Nephroprotective, Antioxidant, Anti-inflammatory Santalaceae Cooling, Skin tonic, Blood purifier Antioxidant, Skin protector, Anti-inflammatory Plumbaginaceae Digestive stimulant, Detoxifier Gastroprotective, Hepatoprotective, Antimicrobial Saxifragaceae Kidney stone dissolver, Diuretic Antilithic, Diuretic, Nephroprotective Vitaceae Bone strengthener, Anti-inflammatory Osteoprotective, Anti-arthritic, Antioxidant Cypereaceae Digestive stimulant, Antipyretic Antipyretic, Gastroprotective, Anti-inflammatory Rosaceae Skin healer, Hormonal balancer Wound healing, Antioxidant, Hormone balancing Anacardiaceae Aphrodisiac, Digestive, Detoxifier Libido-enhancing, Digestive stimulant, Hepatoprotective Symplocaceae Anti-inflammatory, Skin tonic Skin healing, Antimicrobial, Anti-inflammatory Acoraceae Nervine tonic, Memory enhancer Neuroprotective, Cognitive enhancer, Anxiolytic Key Insights: This classification links Ayurvedic karma with modern pharmacology, providing a holistic understanding of herbal propertie References NCISM – Dravyaguna Vigyan NCBI – Ayurvedic Medicinal Plants NCBI – Antioxidant Response of Ayurvedic Plants PubMed – Adaptogenic Properties of Rasayana Herbs Other articles :

Psoriasis globeayush.com
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Psoriasis: Modern and Ayurvedic Perspectives

Psoriasis is a chronic, non-contagious autoimmune skin disorder that accelerates the lifecycle of skin cells, leading to excessive cell buildup and scaling. It affects about 2–3% of the global population, with genetic, immune, and environmental factors playing a key role in its pathogenesis. While modern medicine focuses on immunosuppressants and symptom management, Ayurveda—India’s ancient healing system—provides a holistic approach targeting the root cause through detoxification (Shodhana), herbal therapies (Shamana), and lifestyle modifications. Psoriasis is a chronic, immune-mediated skin disorder that leads to hyperproliferation of keratinocytes, inflammation, and vascular changes. Modern medicine explains psoriasis through genetic, immunological, and environmental factors, while Ayurveda describes it as a Kushta Roga (skin disorder) caused by Dosha imbalance and toxin accumulation. 1. Modern Pathology of Psoriasis Modern science explains psoriasis as a T-cell mediated autoimmune disorder with complex interactions between genetics, immune system dysregulation, and environmental triggers. A. Pathophysiological Process in Psoriasis B. Immunopathology in Psoriasis (Step-by-Step Mechanism) Stage Key Cells Involved Key Cytokines Effects on Skin Initiation Dendritic cells, Macrophages TNF-α, IL-12, IL-23 Activates T-cells T-cell Activation Th1, Th17 IFN-γ, IL-17, IL-22 Inflammation, autoimmunity Keratinocyte Hyperproliferation Keratinocytes IL-17, IL-22, VEGF Thickened skin, scaling Vascular Changes Endothelial cells VEGF Increased blood flow (redness) 2. Ayurvedic Pathology of Psoriasis (Samprapti – Disease Mechanism) A. Tridoshic Imbalance in Psoriasis (Dosha Pathophysiology) Ayurveda classifies psoriasis as Kushta Roga, particularly Ekakushta, Sidhma Kushta, and Kitibha Kushta, caused by an imbalance of Vata, Pitta, and Kapha Doshas. Dosha Involved Effects in Psoriasis Vata (Air & Space) Dryness, scaling, cracking of skin Pitta (Fire & Water) Redness, burning sensation, inflammation Kapha (Earth & Water) Thick plaques, stickiness, pus formation B. Ayurveda’s 6-Stage Disease Progression in Psoriasis Ayurvedic Pathology Stage Modern Equivalent Ayurvedic Explanation Sanchaya (Accumulation of Doshas) Genetic susceptibility Imbalanced Doshas (Vata, Pitta, Kapha) accumulate due to improper diet and lifestyle Prakopa (Aggravation of Doshas) Autoimmune activation Aggravated Doshas circulate in the bloodstream, creating Ama (toxins) Prasara (Spreading of Doshas) T-cell activation Ama spreads to skin and joints, leading to inflammation Sthana Samshraya (Localization in Skin & Joints) Cytokine storm Accumulated toxins settle in weak areas (skin, nails, joints) Vyakti (Manifestation of Symptoms) Psoriatic lesions Red, scaly, thickened plaques with itching Bheda (Chronic Stage with Complications) Psoriatic arthritis, Nail Psoriasis Joint involvement, nail damage, secondary infections C. Role of Agni (Digestive Fire) and Ama (Toxins) in Psoriasis D. Pathological Features of Psoriasis in Ayurveda Ayurvedic Term Meaning in Psoriasis Aswedanam Absence of sweating, dry skin Mahavastu Large affected areas Matsyashakalopamam Fish-like scales on the skin Raktadushti (Blood Toxins) Impaired blood circulation and immune dysfunction Dhatukshaya (Tissue Depletion) Loss of nourishment in skin and joints 3. Comparative Summary of Modern vs. Ayurvedic Pathology of Psoriasis Factor Modern Pathology Ayurvedic Pathology Root Cause Genetic & immune dysfunction Dosha imbalance & toxin accumulation Immune Cells Involved T-cells, Dendritic cells Vata, Pitta, Kapha Key Cytokines TNF-α, IL-17, IL-22 Agni (digestive fire) & Ama (toxins) Skin Changes Epidermal hyperproliferation, inflammation Raktadushti (blood vitiation), Twak Roga (skin disorder) Disease Progression Autoimmune attack on skin & joints Six-stage disease evolution Treatment Focus Suppress immune response (steroids, biologics) Detoxify body (Panchakarma, herbal medicines) 4. Types of Psoriasis Psoriasis is classified into different types based on clinical appearance, location, and severity. Modern medicine categorizes psoriasis based on its immunological and morphological presentation, whereas Ayurveda correlates psoriasis with different types of Kushtha Roga based on Dosha predominance. The table below provides a comparative overview of psoriasis types in modern medicine and Ayurveda, followed by a detailed explanation of each type. Modern Type Characteristics Common Sites Ayurvedic Correlation Dominant Doshas Plaque Psoriasis (Psoriasis Vulgaris) Most common type, raised, red patches with silvery-white scales Scalp, elbows, knees, lower back Ekakushta – Thick, dry patches with scaling Vata-Kapha Guttate Psoriasis Small, drop-like red lesions, triggered by infections Trunk, arms, legs Sidhma Kushta – Small, dry, scaly lesions, often post-infectious Pitta-Vata Inverse Psoriasis Smooth, red, shiny lesions (without scales), occurs in folds Armpits, groin, under breasts, genital areas Charmadala – Red, inflamed, wet lesions in folds Kapha-Pitta Pustular Psoriasis White pustules (blisters) filled with pus, surrounded by red skin Hands, feet, widespread (Generalized) Vidradhi Kushta – Pus-filled blisters and inflamed areas Pitta-Kapha Erythrodermic Psoriasis Severe, widespread redness, peeling, and pain, life-threatening Entire body Vata Rakta – Intense burning, excessive scaling, severe discomfort Vata-Pitta Nail Psoriasis Pitting, discoloration, crumbling, or detachment of nails Nails of fingers and toes Kushta with Ashta Vidha Nidan – Nails affected due to deep-seated toxins Vata-Kapha Psoriatic Arthritis Joint pain, stiffness, swelling along with skin lesions Joints (knees, fingers, spine) Vata Kushta – Arthritis linked to psoriasis due to Vata imbalance Vata-Pitta Detailed Explanation of Each Type 1. Plaque Psoriasis (Psoriasis Vulgaris) – Ekakushta (Vata-Kapha) 2. Guttate Psoriasis – Sidhma Kushta (Pitta-Vata) 3. Inverse Psoriasis – Charmadala (Kapha-Pitta) 4. Pustular Psoriasis – Vidradhi Kushta (Pitta-Kapha) 5. Erythrodermic Psoriasis – Vata Rakta (Vata-Pitta) 6. Nail Psoriasis – Kushta with Ashta Vidha Nidan (Vata-Kapha) 7. Psoriatic Arthritis – Vata Kushta (Vata-Pitta) 4. Modern Medical Treatments for Psoriasis Modern medicine focuses on controlling symptoms, reducing inflammation, and slowing down the rapid turnover of skin cells. Treatment varies based on the severity of psoriasis (mild, moderate, or severe). 1. Topical Treatments (For Mild to Moderate Psoriasis) Topical medications are the first-line treatment for localized psoriasis. They help reduce scaling, inflammation, and itching. A. Corticosteroids (Anti-inflammatory creams & ointments) B. Vitamin D Analogues (Regulates Skin Cell Growth) C. Retinoids (Vitamin A Derivatives) D. Salicylic Acid (Keratolytic Agent) E. Coal Tar (Traditional Remedy) 2. Phototherapy (For Moderate Psoriasis) Light therapy uses ultraviolet (UV) radiation to slow the overactive immune response. A. Narrowband UVB Therapy B. PUVA Therapy (Psoralen + UVA) C. Excimer Laser Therapy 3. Systemic Treatments (For Severe Psoriasis & Psoriatic Arthritis) When psoriasis affects more than 10% of the body or involves the joints (Psoriatic Arthritis), oral or injectable drugs are prescribed. A. Immunosuppressants B. Biologic Therapies (Targeted Immune Modulators) C. Oral Retinoids (For Severe Psoriasis) 4. Lifestyle Modifications Ayurvedic Treatment for Psoriasis (Ekakushta & Kitibha) Ayurveda treats psoriasis by detoxifying the body, balancing

Avascular necrosis
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Avascular Necrosis (AVN) of the Hip

Avascular necrosis (AVN), also known as osteonecrosis, is a condition that occurs when there is a loss of blood supply to the bone, leading to the death of bone cells. It most commonly affects the hip joint, causing debilitating pain, impaired mobility, and potentially leading to joint collapse. In this article, we will explore all aspects of AVN of the hip, including its pathophysiology, risk factors, clinical presentation, diagnostic methods, treatment options, and long-term management strategies. 1. Introduction Avascular necrosis (AVN) of the hip is a serious condition that affects the femoral head, the ball-shaped structure at the top of the femur that fits into the acetabulum of the pelvis to form the hip joint. The loss of blood supply to the femoral head leads to bone cell death, weakening the bone and eventually causing it to collapse. As the bone deteriorates, the joint loses its structural integrity, leading to pain, stiffness, and functional impairment. The hip joint is crucial for weight-bearing activities and is subject to significant mechanical stress during movement. AVN of the hip can severely affect the quality of life, causing chronic pain and disability. The disease is often progressive and may result in osteoarthritis, requiring surgical intervention, most commonly total hip replacement (THR). 2. Pathophysiology of Avascular Necrosis of the Hip The hip joint is highly vascularized, with blood supply provided by branches from the femoral artery, particularly the medial and lateral circumflex arteries. In AVN, there is a disruption in this blood supply, leading to ischemia (lack of blood flow) in the femoral head. Without adequate blood flow, bone cells (osteocytes, osteoblasts, and osteoclasts) are deprived of essential nutrients and oxygen, causing them to die. Over time, the bone structure weakens and collapses, leading to deformities in the hip joint. The initial stage of AVN involves bone cell death and necrosis of trabecular bone, which is the spongy bone inside the femoral head. As the disease progresses, subchondral bone (the bone just beneath the cartilage) is affected, leading to cartilage destruction and joint degeneration. In the final stages, the femoral head can collapse completely, causing severe pain, joint deformity, and loss of function. The collapse of the femoral head results in joint incongruity and a decrease in the congruency between the femoral head and the acetabulum, which impairs the normal function of the hip joint. This damage can lead to secondary osteoarthritis and the development of debilitating hip pain. 3. Risk Factors for Avascular Necrosis of the Hip Several risk factors contribute to the development of AVN of the hip, some of which are modifiable, while others are non-modifiable. Understanding these risk factors is essential for both prevention and early diagnosis. a. Trauma One of the most common causes of AVN is traumatic injury to the hip, such as fractures of the femoral neck or dislocations of the hip joint. Trauma can damage the blood vessels supplying the femoral head, leading to ischemia and necrosis. b. Corticosteroid Use Long-term use of corticosteroids, particularly at high doses, is a well-established risk factor for AVN of the hip. Corticosteroids are thought to cause AVN by several mechanisms, including direct toxicity to osteoblasts, increased intraosseous pressure, and fat embolism that obstructs blood vessels. The risk increases with higher cumulative doses and prolonged use. c. Alcohol Consumption Excessive alcohol intake has been linked to AVN, as it can cause fatty infiltration of the bone marrow and increase intraosseous pressure, leading to compromised blood flow. Chronic alcohol abuse is one of the most significant non-traumatic risk factors for AVN. d. Systemic Diseases Certain systemic diseases are associated with an increased risk of AVN. These include: e. Inherited Conditions Genetic predispositions can also play a role in the development of AVN. For example, individuals with familial hyperlipidemia or those with certain genetic mutations may have an increased risk of developing AVN. f. Other Factors 4. Clinical Presentation The symptoms of AVN of the hip depend on the stage of the disease. In the early stages, patients may experience mild symptoms, while later stages are characterized by severe pain and loss of function. a. Early Stage In the early stages, AVN may be asymptomatic or present with vague symptoms such as mild hip pain or discomfort, which worsens with weight-bearing activities. The pain may be intermittent and is often described as aching or throbbing in nature. It may be localized to the groin, thigh, or buttock. b. Progressive Stage As the disease progresses and bone necrosis increases, patients may experience more persistent pain. The pain becomes more intense, particularly with activity, and may be accompanied by stiffness and limited range of motion. Patients may also experience difficulty walking and may begin to limp. c. Advanced Stage In the advanced stages of AVN, the femoral head may collapse, leading to severe pain and disability. The pain is often constant and can radiate down the thigh or into the knee. Joint movement becomes severely restricted, and patients may have difficulty performing daily activities such as standing, walking, or climbing stairs. 5. Diagnostic Methods Diagnosing AVN of the hip requires a thorough clinical examination, medical history review, and imaging studies. a. Clinical Examination The clinician will perform a physical examination to assess the patient’s range of motion, gait, and tenderness in the hip joint. They may also test for the impingement sign and perform provocative maneuvers to assess for hip joint instability. b. Imaging Studies 6. Treatment Options The treatment of AVN of the hip depends on the stage of the disease, the patient’s age, activity level, and overall health. The goal of treatment is to relieve pain, prevent further bone collapse, and preserve the joint as much as possible. a. Conservative Management b. Surgical Treatment In advanced cases of AVN, surgical intervention is often required. Several surgical options are available, depending on the stage of the disease and the patient’s specific circumstances. 7. Prognosis and Long-Term Management The prognosis of AVN depends on the stage at which the condition is diagnosed and the

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Gait Abnormalities: Over View On Types of Gait Abnormalities

Introduction : Gait: It is a medical term used for the way a person walks . In some people gait is abnormal may be due to some injury or due to under lying medical conditions. Abnormal gait is also called as AMBULATORY DYSFUNCTION. Any thing that affects brain, spinal cord, legs or feet leads to change in gait . Normal Gait : Normal gait is nothing but normal walking without any abnormalities . One complete gait cycle is completed when it begin with heel strike of a foot continues till heel strike of identical foot. Human gait : It can be defined as a series of alternating movements of the lower extremities in a rhythmic motion that results in forward progression of body with minimal energy expenditure . It means it takes 2 steps to complete a full gait cycle. Gait cycle has 2 phases : STANCE PHASE : The time duration of foot on ground , it occupies 60% of gait cycle . It starts when foot touches the ground and ends when the foot leaves the ground. SWING PHASE : The time duration of foot in air, it occupies 40% of gait cycle .I t start when foot leaves the ground and end when same foot touches the ground again. Important support phases : SINGLE SUPPORT PHASE [Swing Phase] : In this phase only one limb is in contact with ground . INITIAL DOUBLE SUPPORT PHASE : It is the sub phase between the heel contact to contralateral foot off. It shows 14 to 20% of stance phase . TERMINAL DOUBLE SUPPORT PHASE : Itis sub phase from contralateral foot on to toe off, It shows 14 to 20% of stance phase . TOTAL DOUBLE SUPPORT PHASE : It shows 28 to 40% of stance phase . As it is the sum of initial double support phase and terminal double support phase . NOTE : More problems will appear during stance phase of gait when foot is loaded which in turn shows impact on the swing phase . The Phases of Human Walking: A Step-by-Step Breakdown GAIT ABNORMALITIES : Most common type , resulted due to pain in lower extremities like pain in muscle , joints or in bones . Limping is seen this type of gait , means avoiding steeping or pressure on affected leg . keeping ankle fixed in the one position while lifting and lowering the foot. This may include following causes like : 2.PROPULSIVE GAIT : It is also called as PARKINSONS GAIT or FESTINATING GAIT . As it is seen in Parkinson’s disease , one can observe stooping means head and neck are bend forwards and downward and rigid posture is seen . Steps are short and fast to maintain center of gravity, hence called as festinating gait .Also seen in carbon monoxide poison . 3 .SCISSORS GAIT : In this type the knees and thighs hits or cross in a scissor like pattern during walk and slow and small steps are seen and this type of gait is diagnosed in spastic cerebral palsy. severe adduction of legs and hitting of the knees and thighs . 4. SPASTIC GAIT : It is also called as hemiplegic gait ,In this type of gait one leg is stiffened while walking . If lifted to walk it is either dragged or swings around in semicircular motion [ circumduction ] . This condition is seen in cerebral palsy , multiple sclerosis , Hemiplegia. 5. STEPPAGE GAIT : It is also called as neuropathic gait ,in this high step is seen means person elevates hip to lift leg higher than normal . Foot appears floppy when it drops and toes point down and scrape ground this type of gait is diagnosed in muscle atrophy or peroneal nerve injury [ like in spinal stenosis or herniated disc ] 6.WADDILING GAIT : In this exaggerate movement of upper body is observed like a duck , hence it is also called as duck walk . This type of gait is diagnosed in hip dislocation , progressive muscular dystrophy. It is also called as myopathic gait . Some times pregnancy women also adopt waddling gait as protective measure to prevent falling. 7. CROUNCHING GAIT : In this gait flexing of ankles, knees and hip is seen while walking . Characteristics like bending down while walking , toe dragging are seen this gait abnormality is diagnosed in cerebral palsy. 8. ATAXIC GAIT : In this irregular steps , person can’t walk in straight line when walk heel to toe [ unsteady walk ]. This abnormality is diagnosed in cerebellar degeneration .Vitamin deficiencies like low levels of vitamin E, B-1, or B-12 and in Sensory disturbances like vision or proprioception disorders 9. SHUFFLING GAIT : In this type of gait feet is not completely lifted off the ground and feet get dragged while walking . This type of gait is seen in medical conditions like Parkinson’s disease , Muscle strain and in nerve damage conditions etc. Symptoms like shot steps ,stooped posture , flexed knees are observed . 10. LURCHING GAIT : This type of gait abnormality is caused due to paralysis or weakness of gluteus muscles or other conditions that affect the hip or legs . In this gait type one may observe slow and long stride . Conclusion : In conclusion, understanding the various types of gait is essential for recognizing and addressing different physical conditions and movement patterns. Gait analysis plays a crucial role in diagnosing and treating mobility issues, whether they stem from neurological disorders, orthopedic injuries, or natural aging. By studying common gait types such as the antalgic, ataxic, and spastic gaits, medical professionals can develop targeted interventions and rehabilitation plans. Additionally, the influence of environmental factors and individual differences in biomechanics further emphasizes the need for personalized care. Overall, analyzing and categorizing gait types not only aids in better medical outcomes but also promotes the importance of early detection and proactive management in maintaining overall mobility and

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Kidney : Anatomy and Clinical Significance

Introduction : Kidneys are a pair of retroperitoneal [covered only on anterior side by peritoneum] organs which are part of excretory system. Location : Situated on the posterior abdominal wall behind the peritoneum, one on each side of vertebral column . It covers epigastric , hypogastric ,lumbar and umbilical regions of abdomen . In vertical view : It covers upper border of 12th Thoracic vertebrae [T12] to center body of 3rd Lumbar vertebrae. NOTE : Right kidney is lower than the Left kidney due to presence of liver on right side . The transpyloric line pass through the upper part of hilus of right kidney and lower part of hilus of left kidney respectively. General Features of Kidney: : External Features of Kidney : It consists of : 2 poles : 2 surfaces : NOTE : It is difficult to recognize anterior and posterior surfaces of kidney . 2 borders : structures coming in and going out of the hilum from anterior to posterior side . Some times , Renal artery may enter hilus behind Renal pelvis and Renal vein tributary may also found in same plane that of renal pelvis. Relations Of Kidney : Relations common in both kidney . Other relations of kidneys : Right kidney : NOTE : Left kidney: NOTE: Coverings of kidney [Capsules] : There are 4 coverings of kidney : Fibrous capsule : It is thin membrane ,closely associate with kidney and lines renal sinus . It is smooth and convex . It can be easily stripped off. But in certain diseases it becomes adherent and cannot stripped off. Perirenal or Perinephric fat : It is a adipose tissue which lines the fibrous capsule ,and it is thickest at borders of kidney and fills up extra space in the renal sinus. It extends over adrenal gland superiorly. Nephroptosis [Floating kidney] : It is the condition in which the absence of perirenal fat or seen in severe loss of weight. Renal Fascia [Gerota’s fascia] : It surrounds the perirenal fat and suprarenal glands [Adrenal gland] . This renal fascia is divided into 2 layers : A number of trabeculae connect the renal fascia to fibrous capsule across perirenal fat. Position of renal fascia : TRACED ABOVE : Two layers meet at the upper pole of kidney and split to enclose suprarenal gland and meet again at upper pole of suprarenal gland continue with fascia covering diaphragm. TRACED BELOW : These two layers remain separate and encloses ureter : LATERALLY: Laterally these layers fuses together and continued with the fascia taransversalis behind colon. MEDIALLY : Pararenal fascia : It is present dorsal to renal fascia , this is more on posterior side to fill paravertebral space and acts cushion. Internal structure of kidney : CORTEX : It consists of two parts : MEDULLA : It is made up of conical masses called renal pyramids 10 in number in each kidney . These form renal papillae at apices and these indent minor calyces which give rise to major calyces and then into renal pelvis . RENAL SINUSES : This is the space extends into kidney from the hilus . It contain RENAL PELVIS : This part gives rise to 2 to 3 major calyces and these give rise to 7 to 13 minor calyces. these minor calyces ends in an expansion which intended by 1 to 3 renal papillae . Structure Of Uriniferous Tubule There are 1 to 3 million tubules in each kidney . These are the structural and functional units of kidney. Each tubule consists of two parts : Excretory part : This part of tubule is called as nephron Collecting part : This is the part where all filtrate finally reaches , this is called as Collecting duct . Many collecting ducts unite and form Ducts of bellini which opens into minor calyces through renal papillae. Juxta Glomerular Apparatus The Juxtaglomerular Apparatus (JGA) are specialized structures in the kidneys that plays a critical role in regulating blood pressure, filtration rate, and electrolyte balance. It is located near the junction of the afferent arteriole and the distal convoluted tubule (DCT) of a nephron. The JGA helps maintain homeostasis, particularly by controlling the renin-angiotensin-aldosterone system (RAAS), which regulates blood volume, blood pressure, and sodium balance. Components of the Juxtaglomerular Apparatus: Blood supply : Vascular Segments : BLOOOD SUPPLY : Lymphatic Drainage : Clinical anatomy NOTE : Kidney stones lie on the body of vertebrae and Gall stones lie on anterior to body of vertebrae. Conclusion: In conclusion, the kidneys are vital organs with critical functions in maintaining the body’s internal balance, including waste filtration, fluid and electrolyte regulation, Control blood pressure , and hormone production. Their clinical anatomy, which involves their structure, location, and functional components, is essential for understanding the mechanisms underlying kidney function and the pathophysiology of kidney diseases. The kidneys’ anatomical features, such as the renal cortex, medulla, nephrons, and blood supply, are closely tied to their physiological roles. Knowledge of kidney anatomy is crucial for diagnosing conditions like chronic kidney disease, acute kidney injury, and kidney stones, as well as for performing medical procedures like biopsies, dialysis, and transplantation. Additionally, understanding congenital and developmental kidney anomalies aids in early diagnosis and management. Overall, understanding of the kidneys’ anatomy and clinical relevance is fundamental in preventing, diagnosing, and managing renal diseases, ensuring better patient outcomes and quality of life. References for more details Websites Books Our Other articles

10 Powerful Meditation Postures to Transform Your Mind and Boost Inner Peace
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10 Powerful Meditation Postures to Transform Your Mind and Boost Inner Peace

Meditation is an ancient practice that offers numerous physical, mental, and spiritual benefits. One of the foundational aspects of effective meditation is adopting the correct posture. A proper posture ensures comfort, stability, and uninterrupted focus during prolonged meditation sessions. This guide provides a detailed exploration of meditation postures, preparatory practices, advanced techniques, and safety precautions for a fulfilling meditative journey. Importance of Proper Meditation Posture A well-aligned meditation posture is not merely about sitting still—it serves as the framework for mental and physical harmony. A proper posture helps: Swami Sivananda states, “Without mastering stability in a meditative posture, progress in meditation and pranayama remains limited. Steadiness in posture cultivates one-pointed concentration, leading to spiritual bliss.” Preparatory Practices for Meditation Before attempting meditation postures, it is essential to prepare the body. The following asanas from the Pawanmuktasana series loosen joints, improve flexibility, and alleviate stiffness: These poses should be practiced daily to enhance the flexibility and endurance required for meditation postures. Foundational Meditation Postures 1. Sukhasana (Easy Pose) 2. Padmasana (Lotus Pose) 3. Ardha Padmasana (Half Lotus Pose) 4. Vajrasana (Thunderbolt Pose) 5. Chair Meditation Advanced Meditation Postures Once a practitioner gains proficiency in foundational postures, advanced techniques can deepen their meditation practice. 1. Siddhasana (Accomplished Pose) 2. Baddha Padmasana (Bound Lotus Pose) Precautions for Meditation Postures To ensure safety and comfort during meditation, follow these precautions: Tips for Enhancing Comfort Conclusion Mastering meditation postures is an essential step toward a fulfilling meditative practice. By practicing preparatory poses, selecting the right posture, and adhering to safety precautions, practitioners can create the perfect conditions for focus, relaxation, and spiritual growth. Further Reading: With patience and dedication, meditation becomes not only a practice but a transformative journey toward inner peace and enlightenment. Other articles :

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